Universität Regensburg

Karl-Michael Schebesch

Anschrift:

Leistungsprofil:

• Fluorescence-guided Neurosurgery (oncologic and vascular)
• Pathophysiology of aneurysmal subarachnoid hemorrhage

• Multicenter, international clinical colaboration within the European Fluorescence Network
• Clinical evaluation of confocal laser-endomicroscopy in neuro-oncologic neurosurgery
• Neuropeptides in subarachnoid hemorrhage - impact on ischemia and neuropsychologic outcome

• Confocal laser-endomicroscope (CONVIVO)
• High end surgical microscope with fluorescence filters BLUE400, YELLOW560, FLOW800
• Fully equipped neurosurgical laboratory

Publikationen:

• Excessive release of endogenous neuropeptide Y into cerebrospinal fluid after treatment of spontaneous subarachnoid haemorrhage and its possible impact on self-reported neuropsychological performance - results of a prospective clinical pilot study on good-grade patients. Bründl E, Proescholdt M, Schödel P, Bele S, Höhne J, Zeman F, Stoerr EM, Brawanski A, Schebesch KM. Neurol Res. 2018 Sep 14:1-13. doi: 10.1080/01616412.2018.1508547
• Fluorescent tracers in neurosurgical procedures: an European survey. Acerbi F, Restelli F, De Laurentis C, Falco J, Cavallo C, Broggi M, Höhne J, Schebesch KM, Schiariti M, Ferroli P. J Neurosurg Sci. 2018 Jul 17. doi: 10.23736/S0390-5616.18.04494-6.
• Extent of Resection in Newly Diagnosed Glioblastoma: Impact of a Specialized Neuro-Oncology Care Center. Haj A, Doenitz C, Schebesch KM, Ehrensberger D, Hau P, Putnik K, Riemenschneider MJ, Wendl C, Gerken M, Pukrop T, Brawanski A, Proescholdt MA. Brain Sci. 2017 Dec 25;8(1). pii: E5. doi: 10.3390/brainsci8010005.
• Treatment of Spontaneous Subarachnoid Hemorrhage and Self-Reported Neuropsychological Performance at 6 Months - Results of a Prospective Clinical Pilot Study on Good-Grade Patients. Bründl E, Schödel P, Bele S, Proescholdt M, Scheitzach J, Zeman F, Brawanski A, Schebesch KM. Turk Neurosurg. 2018;28(3):369-388. doi: 10.5137/1019-5149.JTN.21825-17.0
• Fluorescein-Guided Surgery for Resection of High-Grade Gliomas: A Multicentric Prospective Phase II Study (FLUOGLIO). Acerbi F, Broggi M, Schebesch KM, Höhne J, Cavallo C, De Laurentis C, Eoli M, Anghileri E, Servida M, Boffano C, Pollo B, Schiariti M, Visintini S, Montomoli C, Bosio L, La Corte E, Broggi G, Brawanski A, Ferroli P. Clin Cancer Res. 2018 Jan 1;24(1):52-61. doi: 10.1158/1078-0432.CCR-17-1184
• Fluorescein sodium-guided resection of cerebral metastases-an update. Höhne J, Hohenberger C, Proescholdt M, Riemenschneider MJ, Wendl C, Brawanski A, Schebesch KM. Acta Neurochir (Wien). 2017 Feb;159(2):363-367. doi: 10.1007/s00701-016-3054-3
• Differences in Neuropeptide Y Secretion Between Intracerebral Hemorrhage and Aneurysmal Subarachnoid Hemorrhage. Schebesch KM, Bründl E, Schödel P, Hochreiter A, Scheitzach J, Bele S, Brawanski A, Störr EM, Lohmeier A, Proescholdt M. J Neurosurg Anesthesiol. 2017 Jul;29(3):312-316.
• Treatment of Unruptured Intracranial Aneurysms and Cognitive Performance: Preliminary Results of a Prospective Clinical Trial. Bründl E, Böhm C, Lürding R, Schödel P, Bele S, Hochreiter A, Scheitzach J, Zeman F, Brawanski A, Schebesch KM. World Neurosurg. 2016 Oct;94:145-156. doi: 10.1016/j.wneu.2016.06.112.
• Fluorescein sodium-guided surgery in cerebral lymphoma. Schebesch KM, Hoehne J, Hohenberger C, Acerbi F, Broggi M, Proescholdt M, Wendl C, Riemenschneider MJ, Brawanski A. Clin Neurol Neurosurg. 2015 Dec;139:125-8. doi: 10.1016/j.clineuro.2015.09.015.

Kooperationsangebot für die Wirtschaft / Praxis:

• Further development and improvement of intraoperative fluorescence techniques, including confocal laser-endomicroscopy
• Validation and establishment of new outcome measurements for aneurysmal subarachnoid hemorrhage

Bestehende Kooperationen: