Universität Regensburg

Oliver Bosch

Anschrift:

Leistungsprofil:

• Zustandekommen einer gestörten Mutter-Kind Bindung; Studien im Nagermodell; Fokus auf Stress-System und Interaktionen mit anderen Neurostransmittern
• Auswirkungen des Verlusts des Partners oder des Nachwuchs auf emotionaler und physiologischer Ebene im Nager; Suche nach Möglichkeiten die negativen Effekte umzukehren

• Verhaltensstudien
• intrazerebrale Infusionen
• molekulare Ansätze

Publikationen:

• Klampfl SM, Schramm MM, Gaßner BM, Hübner K, Seasholtz AF, Brunton PJ, Bayerl DS, Bosch OJ (2018) Maternal stress and the MPOA: Activation of CRF receptor 1 impairs maternal behavior and triggers local oxytocin release in lactating rats. Neuropharmacology 133: 440-450.
• Bosch OJ, Pohl TT, Neumann IN, Young LJ (2018) Abandoned prairie vole mothers show normal maternal care but altered emotionality: Potential influence of the brain corticotropin-releasing factor system. Behav Brain Res 341: 114-121.
• Klampfl SM, Schramm MM, Stinnett GS, Bayerl DS, Seasholtz AF, Bosch OJ (2016) CRF-binding protein modulates aspects of maternal behavior under stressful conditions and supports a hypo-anxious state in lactating rats. Horm Behav 84: 136-144.
• Klampfl SM, Bosch OJ (2019) Mom doesn't care: when increased brain CRF system activity leads to maternal neglect in rodents. Front Neuroendocrinol 53: 100735.
• Klampfl SM, Brunton PJ, Bayerl DS, Bosch OJ (2016) CRF-R1 activation in the anterior-dorsal BNST induces maternal neglect in lactating rats via an HPA axis-independent central mechanism. Psychoneuroendocrinology 64: 89-98.
• Pohl TT, Young LJ Bosch OJ (2018) Lost connections: Oxytocin and the neural, physiological and behavioural consequences of disrupted relationships. Int J Psychophysiology doi: 10.1016/j.ijpsycho.2017.12.011.
• Bosch OJ, Young LJ (2017) Oxytocin and social relationships: From attachment to bond disruption. Curr Top Behav Neurosci doi:10.1007/7854_2017_10.
• Bosch OJ, Dabrowska J, Modi ME, Johnson ZV, Keebaugh AC, Barrett CE, Ahern TH, Guo JD, Grinevich V, Rainnie DG, Neumann ID, Young LJ (2016) Oxytocin in the nucleus accumbens shell reverses CRFR2-evoked passive stress-coping after partner loss in monogamous male prairie voles. Psychoneuroendocrinology 64: 66-78.
• Bosch OJ, Nair HP, Ahern TH, Neumann ID, Young LJ (2009) The CRF system mediates increased passive stress-coping behavior following the loss of a bonded partner in a monogamous rodent. Neuropsychopharmacology 34: 1406-1415.
• Bosch OJ, Neumann ID (2008) Brain vasopressin is an important regulator of maternal behavior independent of dams' trait anxiety. PNAS 105: 17139-17144.

Kooperationsangebot für die Wirtschaft / Praxis:

Bestehende Kooperationen: